Thermo Fisher Scientific GPX4 Polyclonal Antibody
Human GPX4 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500–1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 glycerol 버퍼에 보관. 세포 산화 손상 보호 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GPX4. Recombinant protein control fragment (Product # RP-104833) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791014 |
Product Specific Information
Immunogen sequence:
NVKFDMFSKI CVNGDDAHPL WKWMKIQPKG KGILGNAIKW NFTKFLIDKN GCVVKRYGPM EEPLVIEKDL PHY
Target Information
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage.
Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine.
Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm.
In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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