Thermo Fisher Scientific FOLH1/PSMA (Prostate Epithelial Marker) Monoclonal Antibody (FOLH1/2121)
인간 FOLH1/PSMA 단백질을 인식하는 마우스 단일클론 항체로, 전립선 상피 표지자로 사용됩니다. ELISA 등 다양한 연구 응용 가능하며, Protein A/G로 정제된 액상 형태입니다. 4°C 보관, 동결 금지.
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Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FOLH1/2121 |
| Immunogen | Recombinant human FOLH1 protein fragment (around aa 232–433) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on various substrates, including folate and the neuropeptide N-acetyl-L-aspartyl-L-glutamate. It is expressed in tissues such as the prostate, central and peripheral nervous system, and kidney. Mutations may cause impaired intestinal absorption of folates leading to low blood folate levels and hyperhomocysteinemia. In the brain, expression may be associated with glutamate excitotoxicity-related conditions. In the prostate, the protein is up-regulated in cancerous cells and serves as a diagnostic and prognostic marker for prostate cancer. This gene likely arose from a duplication event, and alternative splicing yields multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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