Thermo Fisher Scientific Sutimlimab Chimeric Recombinant Human Monoclonal Antibody

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Human / IgG4, kappa

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Immunogen

Human C1S

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.05 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911333

Product Specific Information

Endotoxin level < 0.01EU/µg by LAL method

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

Target Information

Sutimlimab is an anti-C1s antibody. Studies have shown that it can significantly increase hemoglobin levels in patients with primary cold agglutinin disease. Cold agglutinin disease (CAD) is a type of acquired autoimmune hemolytic anemia (AIHA). In cold environments, cold parts of the body will have clinical symptoms related to red blood cell aggregation (for example, the Internet Plaque or cyanosis) and hemolytic anemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.