Thermo Fisher Scientific GABA B Receptor1 Polyclonal Antibody
Rabbit polyclonal antibody against GABA B Receptor1 for IHC applications. Unconjugated liquid form with undefined concentration. Stored at -20°C and shipped on wet ice. Suitable for research use only, not for diagnostic purposes.
- 카탈로그번호
- RA20003-100UL
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GABA B Receptor1 Polyclonal Antibody
Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | EKENRELEKIIAEKEERVSELRH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulate phospholipase A2, activate potassium channels, inactivate voltage-dependent calcium channels, and modulate inositol phospholipid hydrolysis. Plays a critical role in fine-tuning inhibitory synaptic transmission.
Pre-synaptic GABA-B-R inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies late inhibitory postsynaptic potentials. Implicated in synaptic inhibition, hippocampal long-term potentiation, slow wave sleep, muscle relaxation, and antinociception.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.