Thermo Fisher Scientific Ki67 Monoclonal Antibody (OTI3D11), TrueMAB
Ki-67 단백질을 표적하는 마우스 단클론 항체로 세포 증식 마커 분석에 적합. Western blot과 파라핀 조직 면역조직화학(IHC)에 사용 가능. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도. 연구용으로만 사용.
- 카탈로그번호
- TA500265
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Ki67 Monoclonal Antibody (OTI3D11), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D11 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 1–250 of human MKI67 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ki-67 is a nuclear protein expressed during various stages of the cell cycle, particularly in late G1, S, G2, and M phases. It contains a forkhead-associated (FHA) domain that mediates association with euchromatin at the perichromosomal layer, centromeric heterochromatin, and nucleolus. Ki-67 shows cell cycle-dependent localization: perinucleolar in G1, nuclear matrix in G2, and chromosomal during M phase.
This protein is widely used as a proliferation marker since it is absent in G0 cells and increases from G1 through mitosis. Ki-67 antibodies help determine the growth fraction in neoplasms and correlate with tumor grade. It is also routinely used as a neuronal marker for cell cycling and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.