Thermo Fisher Scientific HDAC1 Polyclonal Antibody, Alexa Fluor 555
HDAC1 단백질을 검출하기 위한 Alexa Fluor 555 결합 폴리클로날 항체. 인간, 마우스, 랫, 햄스터, 개 조직 및 세포에 적용 가능. 면역세포형광염색(ICC/IF)에 적합하며, 4°C 암소 보관. 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues C E(467) E K P E A K G V K E E V K L A(482) of human HDAC1 |
| Conjugate | Alexa Fluor™ 555 |
| Excitation / Emission Max | 553 / 568 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Wet ice |
| RRID | AB_2663463 |
Product Specific Information
PA1860A555 detects histone deacetylase 1 (HDAC1) from human, mouse, rat, hamster, and canine tissues and cells.
The immunogen is a synthetic peptide corresponding to residues C E(467) E K P E A K G V K E E V K L A(482) of human HDAC1.
This immunizing peptide (Cat. # PEP-069) is available for use in neutralization and control experiments.
Target Information
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in regulating eukaryotic gene expression.
HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex.
It interacts with retinoblastoma tumor-suppressor protein, forming a complex that controls cell proliferation and differentiation.
Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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