Thermo Fisher Scientific Human GNAI1/GNAI2 (aa 346-355) Synthetic Peptide

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Class

Synthetic

Type

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

purified

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

PEP-129 is a 10 amino acid synthetic peptide whose sequences are derived from human G protein alpha inhibitor 1/2 protein. The sequence of this peptide is (amino to carboxy terminus): K (346)-N-N-L-K-D-C-G-L-F (355)

This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human G protein alpha inhibitor 1/2, catalog # PA1-1000. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.

Reconstitute with 0.1 mL of distilled water.

Target Information

The G protein family of signal transducers includes the alpha, beta, gamma subunits and the effector which are most clearly distinguished by their different alpha chains. The family also includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein of unknown function that is abundantly expressed in brain; and transducin 1 and 2, proteins involved in retinal phototransduction. The G proteins possess GTPase activity and are components of a complex membrane signaling system that includes membrane-bound receptors. The system exists to modulate extracellular signals as they are transmitted into the cell.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.