Thermo Fisher Scientific SPHK1 Polyclonal Antibody, Biotin
SPHK1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Biotin 결합 폴리클로날 항체입니다. Western blot, IHC, ELISA, IP 등 다양한 응용에 사용 가능하며, 인간 및 설치류 등 여러 종에 반응합니다. 고순도 친화 크로마토그래피 정제, 안정적인 액상 형태로 연구용에 적합합니다.
- 카탈로그번호
- SPHK1-BIOTIN
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific SPHK1 Polyclonal Antibody, Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 50–100 on human SPHK1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine to produce sphingosine-1-phosphate (S1P), a key signaling molecule. S1P acts through G-protein coupled receptors to regulate cellular processes such as differentiation, calcium mobilization, and apoptosis. Inhibitors of SPHKs are considered potential therapeutics for cancer treatment. S1P also interacts with EDG family G protein-coupled receptors (S1P receptors).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(SPHK1-BIOTIN_SP HK1_Q9NYA1-1_Rabbit.svg 및 SPHK1-BIOTIN_SP HK1_Q9NYA1-1_Rabbit_PDP.jpeg 이미지 포함)
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