Thermo Fisher Scientific IFITM3 Polyclonal Antibody
IFITM3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, IP 등 다양한 응용에 사용 가능. Mouse와 Rat에 반응하며, 항원 친화 크로마토그래피로 정제. 액상 형태로 4°C 보관, 장기 보관 시 -20°C 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.25–1 µg/mL | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 10 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 5–10 µg/mL | - |
| Flow Cytometry (Flow) | - | 1 publication |
| Immunoprecipitation (IP) | Assay-Dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from residues 1–50 of Mouse Fragilis |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551950 |
Product Specific Information
Immunohistochemistry has been used successfully with glycolmethacrylate sections.
Target Information
IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein belonging to the IFITM family. These proteins are induced by type I and II interferons and contain multiple IFN-stimulated response elements (ISREs) in their promoters. IFITM proteins are involved in various cellular processes such as anti-proliferative activities and cell adhesion, and their expression depends on SWI/SNF-like BAF chromatin remodeling complexes. IFITM genes are often upregulated in cancer cells, suggesting a role in carcinogenesis. IFITM3, a 133 amino acid membrane protein, is induced by IFN-α and IFN-γ and regulated by TEF-1, Brg-1, and Sp1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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