Thermo Fisher Scientific KLF15 Polyclonal Antibody
KLF15 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체. WB 및 Flow Cytometry에 사용 가능하며 인간, 쥐, 돼지, 마우스 반응 예측. 0.5 mg/mL 농도의 액상 형태로, TBS 버퍼와 BSA 포함. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
- View 1 publication
Flow Cytometry (Flow)
- Tested Dilution: 10 µg/mL
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (VDHLLPVDENFSS) corresponding to the N-terminus amino acids of KLF15 (aa 2–15) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10982122 |
Product Specific Information
- Predicted to react with mouse, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
KLF15 is a nuclear protein belonging to the Sp1 C2H2-type zinc-finger protein family with three C2H2-type zinc fingers. It acts as a transcriptional activator binding to the GA element of the CLCNKA promoter, regulating tissue- and nephron-specific expression of CLCNKA and CLCNKB channel genes.
KLF15 plays an essential role in adipogenesis through regulation of PPARG expression, inhibits cardiac hypertrophy, and modulates mitochondrial acetyl-CoA synthase expression in skeletal muscle. It may also repress rhodopsin and IRBP promoters in the retina, contributing to photoreceptor gene regulation.
Highly expressed in liver, heart, skeletal muscle, and kidney; not expressed in bone marrow or lymphoid tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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