Thermo Fisher Scientific GPR17 Monoclonal Antibody (OTI6A3), TrueMAB
인간 GPR17 단백질을 인식하는 마우스 단일클론 항체로, IHC(P) 실험에 적합합니다. TrueMAB 형식으로 높은 특이성과 재현성을 제공합니다. 액상 형태로 공급되며, -20°C 보관이 필요합니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6A3 |
| Immunogen | Synthetic peptide within Human GPR17 C-terminal (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The G-protein-coupled receptor (GPCR) superfamily consists of approximately 600–1,000 members and represents the largest class of molecular targets with proven therapeutic value.
GPR17 is an orphan G protein-coupled receptor involved in the orchestration of oligodendrocyte differentiation and myelination in the central nervous system.
It is expressed in brain, kidney, heart, and umbilical vein endothelial cells.
GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) with inhibition of adenylyl cyclase.
It may mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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