Thermo Fisher Scientific TCF3/TCF4 Monoclonal Antibody (6F12-3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

6F12-3

Immunogen

His-tagged fusion protein corresponding to residues 31-331 of human TCF4. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TCF3/TCF4,uniProtId:P15884-1,ncbiNodeId:9606,antigenRange:31-331,antigenLength:667,antigenImageFileName:MA1-25418_TCF3TCF4_P15884-1_House_mouse.svg,antigenImageFileNamePDP:MA1-25418_TCF3TCF4_P15884-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.53 mg/mL

Purification

Protein G

Storage buffer

TBS, pH 7.4, with 30% glycerol

Contains

0.08% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_795485

Product Specific Information

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

TCF 4 (T cell factor 4) is a member of the TCF/LEF (lymphoid enhancer factor) family of transcription factors. Members of this family along with b catenin, are involved in mediating Wnt signaling by transactivating downstream genes. TCF 4 generates transcriptionally active complexes with b catenin in colon carcinoma cells. Expression of TCF 4 is highest in the CNS and intestinal epithelium where Wnt signaling also plays an essential role in development. Aberrant TCF 4 transcription activity has been implicated in carcinogenesis of intestinal and mammary epithlia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.