Thermo Fisher Scientific AANAT Polyclonal Antibody
Rabbit polyclonal antibody against human AANAT for ICC/IF applications. Recognizes recombinant human Serotonin N-AT. Purified by antigen affinity chromatography. Supplied in PBS with 40% glycerol, 0.02% sodium azide. For research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Serotonin N-AT (Recombinant protein control fragment, Product #RP-106527) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663390 |
Product Specific Information
Immunogen sequence:
FLTLCPELSLG WFEEGCLVAF IIGSLWDKER LMQESLTLHR SGGHIAHLHV LAVHRAFRQQ GRGPILLWR
- Highest antigen sequence identity to orthologs: mouse 89%, rat 89%
Target Information
Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme in melatonin synthesis. Melatonin regulates sleep and circadian rhythm. AANAT levels vary significantly between day and night, influencing melatonin synthesis in the pineal gland and retina.
Research suggests that AANAT activity can be regulated by protein levels and by alternative mechanisms affecting melatonin production without altering AANAT protein abundance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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