Thermo Fisher Scientific RASA2 Polyclonal Antibody
Human RASA2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관. 연구용으로 세포 신호전달 연구에 적합.
- 카탈로그번호
- PA557248
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RASA2. Recombinant protein control fragment (Product # RP-96380) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646323 |
Product Specific Information
Immunogen sequence:
SLSKSKSSFK ETFMCEFFKM FQEEGYIIAV KKFLDEISST ETKESSGTSE PVHLKEGEMY KRAQGRTRIG K
Highest antigen sequence identity to orthologs:
- Mouse: 82%
- Rat: 82%
Target Information
The Ras-related low molecular mass GTPases participate in signal transduction involving various cellular functions, including cell-cycle progression, cellular differentiation, cytoskeletal organization, protein transport, and secretion.
The Ras-GTPase-activating protein (RASGAP) forms a complex with a second protein, p190, in growth factor-stimulated and tyrosine kinase-transformed cells.
The RASGAP–p190 complex may serve to couple Ras- and Rho-mediated signaling pathways.
RASGAP forms an abundant SH2-mediated complex with p190 RhoGAP in cells expressing activated tyrosine kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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