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Thermo Fisher Scientific LRP6 Polyclonal Antibody
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LRP6 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC 등 다양한 응용에 적합합니다. 인간 시료에 반응하며, 친화 크로마토그래피로 정제되었습니다. PBS와 50% 글리세롤에 보관되며, 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오후 03:31
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Thermo Fisher Scientific PA5115523 LRP6 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
655,000원VAT 포함 720,500원
Thermo Fisher Scientific · Thermo Fisher Scientific LRP6 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LRP6 (Accession O75581), corresponding to amino acid residues G1454–Y1504 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900159 |
Product Specific Information
Antibody detects endogenous levels of total LRP6.
Target Information
LRP6 is essential for the Wnt/beta catenin signaling pathway, acting as a coreceptor with Frizzled for Wnt. It serves as a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. Interaction with DKK1 inhibits LRP6-mediated Wnt/beta catenin signaling through Kremen protein–mediated endocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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