Thermo Fisher Scientific JLP Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
NLSGGKTRDG GSVVGASVFY KDVAGLDTEG SKQRSASQSS LDKLDQELKE QQKELKNQEE LSSLVWICTS THSATKVL

Target Information

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells.
The protein is a calcium(2+)-independent cell-cell adhesion molecule belonging to the immunoglobulin superfamily, with 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region.
It acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus, mediating viral entry into epithelial and neuronal cells.
Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate.
Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.