Thermo Fisher Scientific TCF19 Polyclonal Antibody
TCF19 단백질(Transcription Factor 19)을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western Blot 및 ELISA에 적합하며, 고순도의 Affinity Chromatography로 정제된 액상 형태입니다. 세포주기 관련 연구용으로 최적화된 시약입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–290 of human TCF19 (NP_009040.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855879 |
Product Specific Information
Immunogen sequence:
MLPCFQLLRI GGGRGGDLYT FHPPAGAGCT YRLGHRADLC DVALRPQQEP GLISGIHAEL HAEPRGDDWR VSLEDHSSQG TLVNNVRLPR GHRLELSDGD LLTFGPEGPP GTSPSEFYFM FQQVRVKPQD FAAITIPRSR GEARVGAGFR PMLPSQGAPQ RPLSTFSPAP KATLILNSIG SLSKLRPQPL TFSPSWGGPK SLPVPAPPGE MGTTPSAPPQ RNRRKSVHRV LAELDDESEP PENPPPVLME PRKKLRVDKA PLTPTGNRRG RPRKYPVSAP MAPPAVGGGE
Target Information
TCF-19 (transcription factor 19), also known as SC1 or SC1-1, is a 345 amino acid nuclear protein containing one FHA domain, a proline-rich domain, and one PHD-type zinc finger. It functions as a trans-activating factor involved in transcription of genes regulating late stages of cell cycle progression (G1 to S transition or entry into G2 and mitosis). TCF-19 expression peaks in the G1-S phase. The gene localizes to chromosome 6, a region associated with psoriasis vulgaris, suggesting a role in epidermal cell hyperproliferation and disease development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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