Thermo Fisher Scientific ACVRL1 Monoclonal Antibody (OTI5C2), TrueMAB
ACVRL1 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 최적화됨. Human ACVRL1(aa 22-119) 재조합 단백질을 면역원으로 사용. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 완충액에 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific ACVRL1 Monoclonal Antibody (OTI5C2), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution
- 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–119 of human ACVRL1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1 has a conserved serine-threonine kinase subdomain, a GS domain preceding the kinase domain, and a short C-terminal tail.
Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2 and have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by ectopic bone formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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