Thermo Fisher Scientific TMPRSS2 Polyclonal Antibody
TMPRSS2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 유세포분석에 사용 가능. 인간 및 마우스 반응성 확인. 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Flow Cytometry (Flow) | 1:10–1:50 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 314–343 of the central region of human TMPRSS2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2272011 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
TMPRSS2 is a serine protease that contains a type II transmembrane domain, receptor class A domain, scavenger receptor cysteine-rich domain, and protease domain. It is involved in various physiological and pathological processes. TMPRSS2 expression is up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain is cleaved and secreted into the cell medium after autocleavage.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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