Thermo Fisher Scientific PAPD5/TRF4-2 Polyclonal Antibody
PAPD5/TRF4-2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 면역침강(IP)에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PAPD5/TRF4-2 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of human PAP-associated domain-containing protein 5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Terminal nucleotidyltransferase that catalyzes preferentially the transfer of ATP and GTP on RNA 3′ poly(A) tail, creating a heterogeneous 3′ poly(A) tail that stabilizes mRNAs by protecting them from active deadenylation (PubMed:21788334, PubMed:30026317).
Also functions as a catalytic subunit of a TRAMP-like complex with poly(A) RNA polymerase activity involved in post-transcriptional quality control.
Required for cytoplasmic polyadenylation of mRNAs involved in carbohydrate metabolism, including glucose transporter SLC2A1/GLUT1 (PubMed:28383716).
Plays a role in replication-dependent histone mRNA degradation, possibly through terminal uridylation of mature histone mRNAs.
Mediates 3′ adenylation of microRNA MIR21 and H/ACA box snoRNAs, influencing stability and maturation (PubMed:25049417, PubMed:22442037).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.