Thermo Fisher Scientific POLR1B Monoclonal Antibody (4H6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

4H6

Immunogen

POLR1B (NP_061887, 963 a.a. approximately 1072 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:POLR1B,uniProtId:Q9H9Y6-1,ncbiNodeId:9606,antigenRange:963-1072,antigenLength:1135,antigenImageFileName:H00084172-M10_POLR1B_Q9H9Y6-1_House_mouse.svg,antigenImageFileNamePDP:H00084172-M10_POLR1B_Q9H9Y6-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: GEMLKAAGYN FYGTERLYSG ISGLELEADI FIGVVYYQRL RHMVSDKFQV RTTGARDRVT NQPIGGRNVQ GGIRFGEMER DALLAHGTSF LLHDRLFNCS DRSVAHVCVK

Target Information

Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.