Thermo Fisher Scientific PTK7 Monoclonal Antibody (4F5)
PTK7 단백질을 인식하는 Mouse monoclonal antibody (clone 4F5). Western blot, ICC/IF, ELISA에 적합하며 인간 시료 반응성. PBS(pH 7.4) 용액 형태로 제공되며 보존제 무첨가. -20°C에서 보관하며 동결·해동 반복은 피해야 함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F5 |
| Immunogen | PTK7 (NP_002812, 36 a.a. ~145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
KQPSSQDALQ GRRALLRCEV EAPGPVHVYW LLDGAPVQDT ERRFAQGSSL SFAAVDRLQD
SGTFQCVARD DVTGEEARSA NASFNIKWIE AGPVVLKHPA SEAEIQPQTQTarget Information
CCK4 may function as a cell adhesion molecule. Although it belongs to the insulin receptor subfamily of the Tyr protein kinases, it likely lacks the catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or may represent a tumor progression marker.
This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta, and melanocytes, but weakly expressed in thyroid gland, ovary, brain, heart, and skeletal muscle, and not in colon. It is also expressed in erythroleukemia cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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