Thermo Fisher Scientific RPL29/Ribosomal Protein L29 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:10,000–1:25,000

Immunoprecipitation (IP)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, predicted to react with Mouse, Rat, Bovine, and Pig

Target Information

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation.
Different members of this family show distinct substrate specificities for MAPKs, varied tissue distribution and subcellular localization, and different inducibility modes by extracellular stimuli.
This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. It is evenly distributed in both the cytoplasm and nucleus and is widely expressed in various tissues and organs, with expression elevated by stress stimuli.
Three transcript variants encoding two different isoforms have been found for this gene.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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