Thermo Fisher Scientific STMN4 Polyclonal Antibody
STMN4 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 최적화됨. 인간 STMN4 C-말단 합성 펩타이드로 면역화. 액상 형태, 농도 1 mg/mL, -20°C 보관. 신경세포 특이적 단백질 연구에 적합.
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Thermo Fisher Scientific STMN4 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the C-terminal region of human STMN4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556059 |
Target Information
RB3 (Stathmin-4), encoded by the STMN4 gene, is a neuron-specific homologue of the SCG10/stathmin family proteins. It possesses a unique N-terminal membrane-associated domain and a stathmin-like domain at the C terminus, which promotes microtubule (MT) catastrophe and/or tubulin sequestering.
Stathmin is a ubiquitous cytosolic phosphoprotein, preferentially expressed in the nervous system, acting as a relay integrating diverse intracellular signaling pathways. RB3 is consistently up-regulated in differentiated neuroblastoma cells, and stable expression of transfected RB3 can induce differentiation, suggesting its role during neuroblastoma differentiation. Moreover, increased RB3 is a unique response protein among stathmin-related proteins following optic nerve axotomy and may be a critical target in neurodegenerative disease research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-39485_STMN4_Q9H169-1_Rabbit.svg / PA5-39485_STMN4_Q9H169-1_Rabbit_PDP.jpeg)
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