Thermo Fisher Scientific GPI Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL
• Publications: [References not provided]

Product Specifications

Product Specific Information

Immunogen sequence:
VINIGIGGSD LGPLMVTEAL KPYSSGGPRV WYVSNIDGTH IAKTLAQLNP ESSLFIIASK TFTTQETITN AETAKEWFLQ AAKDPSAVAK HFVALST

Target Information

This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways.
The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate.
It functions both inside and outside the cell:

• In the cytoplasm, it participates in glycolysis and gluconeogenesis.
• Outside the cell, it acts as a neurotrophic factor for spinal and sensory neurons.

Defects in this gene can cause nonspherocytic hemolytic anemia, and severe enzyme deficiency may lead to hydrops fetalis, neonatal death, and neurological impairment.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.