Thermo Fisher Scientific BRD2 Polyclonal Antibody
Thermo Fisher Scientific의 BRD2 Polyclonal Antibody는 인간 BRD2 단백질을 인식하는 토끼 다클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 고순도 정제 및 안정한 PBS 버퍼에 보관되며, BRD2 단백질 연구에 활용됩니다.
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- PA515297
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 170–200 of the central region of human BRD2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2065878 |
Product Specific Information
This antibody is predicted to react with bovine, mouse, and rat based on sequence homology.
Target Information
The BRD2 gene encodes a transcriptional regulator of the BET (bromodomain and extra-terminal domain) family. This protein associates with transcription complexes and acetylated chromatin during mitosis, selectively binding to acetylated lysine-12 of histone H4 via its two bromodomains.
Located in the MHC class II region on chromosome 6p21.3, BRD2 is not directly involved in immune response but has been implicated in juvenile myoclonic epilepsy. Multiple alternatively spliced variants exist, though some remain incompletely characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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