Thermo Fisher Scientific MMP28 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MVARVGLLLR ALQLLLWGHL DAQPAERGGQ ELRKEAEAFL EKYGYLNEQV PKAPTSTRFS DAIRAFQWVS QLPVSGVLDR ATLRQMTRPR CGVTDTNSYA AWAERISDLF ARHRTKMRRK KRFAKQGNKW YKQHLSYRLV NWPEHLPEPA VRGAVRAAFQ LWSNVSALEF WEAPATGPAD IRLTFFQGDH NDGLGNAFDG PGGALAHAFL PRRGEAHFDQ DERWSLSRRR GRNLFVVLAH EIGHTLGLTH SPAPRALMAP YYKRLGRDAL LSWDDVLAVQ SLYGKPLGGS VAVQLPGKLF TDFETWDSYS PQGRRPETQG PKYCHSSFDA ITVDRQQQLY IFKGSHFWEV AADGNVSEPR PLQERWVGLP PNIEAAAVSL NDGDFYFFKV QSV

Target Information

Epilysin, also known as matrix metalloproteinase-28 (MMP-28), is a secreted protein belonging to the peptidase M10A family. Matrix metalloproteinases are responsible for extracellular matrix degradation, essential for tissue remodeling, reproduction, and embryonic development.
Epilysin is produced by proliferating keratinocytes and mediates degradation of casein. Its expression increases in response to skin injury, suggesting a role in tissue repair and homeostasis. It may also function in the nervous system; incubation with rat embryonic brain tissue leads to myelin protein degradation. In Xenopus, Epilysin localizes to nerves and is upregulated during neurulation, indicating a conserved role in neural development and extracellular matrix modulation.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.