Thermo Fisher Scientific MMP28 Polyclonal Antibody, MaxPab
Rabbit polyclonal antibody targeting human MMP28 (Epilysin). Validated for Western blot with 1–5 µg/mL dilution. Useful for studying extracellular matrix remodeling and neural development. Supplied as liquid, unconjugated, affinity-purified, stored at ...
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Applications
- Western Blot (WB): 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | MMP28 (AAH02631, 1 a.a. ~393 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MVARVGLLLR ALQLLLWGHL DAQPAERGGQ ELRKEAEAFL EKYGYLNEQV PKAPTSTRFS DAIRAFQWVS QLPVSGVLDR ATLRQMTRPR CGVTDTNSYA AWAERISDLF ARHRTKMRRK KRFAKQGNKW YKQHLSYRLV NWPEHLPEPA VRGAVRAAFQ LWSNVSALEF WEAPATGPAD IRLTFFQGDH NDGLGNAFDG PGGALAHAFL PRRGEAHFDQ DERWSLSRRR GRNLFVVLAH EIGHTLGLTH SPAPRALMAP YYKRLGRDAL LSWDDVLAVQ SLYGKPLGGS VAVQLPGKLF TDFETWDSYS PQGRRPETQG PKYCHSSFDA ITVDRQQQLY IFKGSHFWEV AADGNVSEPR PLQERWVGLP PNIEAAAVSL NDGDFYFFKV QSV
Target Information
Epilysin, also known as matrix metalloproteinase-28 (MMP-28), is a secreted protein belonging to the peptidase M10A family. Matrix metalloproteinases are responsible for extracellular matrix degradation, essential for tissue remodeling, reproduction, and embryonic development.
Epilysin is produced by proliferating keratinocytes and mediates degradation of casein. Its expression increases in response to skin injury, suggesting a role in tissue repair and homeostasis. It may also function in the nervous system; incubation with rat embryonic brain tissue leads to myelin protein degradation. In Xenopus, Epilysin localizes to nerves and is upregulated during neurulation, indicating a conserved role in neural development and extracellular matrix modulation.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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