Thermo Fisher Scientific Ki-67 Polyclonal Antibody
Thermo Fisher Scientific의 Ki-67 Polyclonal Antibody는 세포 증식 마커로 널리 사용됩니다. 마우스 Ki-67 단백질에 반응하며, Rabbit IgG 폴리클로날 항체입니다. IHC 및 IHC(P)에서 1:100~1:500 희석으로 사용 가능합니다. 항원 친화 크로마토그래피로 정제된 액상 형태입니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Ki-67 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1650 and 1700 of mouse Ki-67 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Ki-67 is a nuclear protein expressed during various stages of the cell cycle, particularly in late G1, S, G2, and M phases. It contains a forkhead-associated (FHA) domain that allows association with euchromatin at the perichromosomal layer, centromeric heterochromatin, and nucleolus.
Ki-67 shows a cell cycle-dependent distribution:
- G1 phase: perinucleolar expression
- G2 phase: nuclear matrix expression
- M phase: chromosomal expression
As Ki-67 is absent in G0 cells but increases through mitosis, it is widely used as a proliferation marker to determine the growth fraction of neoplasms. The Ki-67 index correlates strongly with tumor grade and is a valuable prognostic indicator. It is also used as a neuronal marker for cell cycling and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.