Thermo Fisher Scientific BID Polyclonal Antibody
Thermo Fisher Scientific BID Polyclonal Antibody는 인간 BID 단백질을 검출하는 토끼 유래 IgG 항체입니다. WB, IHC, IP 등 다양한 응용에 적합하며, 액상 형태로 제공됩니다. BID의 세포 사멸 관련 연구에 활용 가능하며, 안정적인 장기 보관이 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–4 µg/mL |
| Immunohistochemistry (IHC) | 20–40 µg/mL |
| Immunoprecipitation (IP) | 5–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the region surrounding amino acid 37 of human Bid |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_779415 |
Product Specific Information
PA1-26454 detects Bid from human samples.
Target Information
BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. It is a member of the BCL-2 family of cell death regulators and mediates mitochondrial damage induced by caspase-8 (CASP8). CASP8 cleaves BID, and the COOH-terminal fragment translocates to mitochondria, triggering cytochrome c release and apoptosis. BID serves as a molecular link between caspase-8 activation and mitochondrial death machinery.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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