Thermo Fisher Scientific SCUBE1 Polyclonal Antibody
Thermo Fisher Scientific의 SCUBE1 폴리클로날 항체로, 마우스 SCUBE1 단백질의 C-말단 합성 펩타이드에 특이적입니다. Western blot에 최적화되어 있으며, 높은 종간 상동성(100%)을 보입니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of mouse SCUBE1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689555 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 100%
Target Information
SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm, and limb buds.
The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca²⁺-dependent fashion.
In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity.
Genetic ablation of this region resulted in brain malformation in mouse embryos, suggesting SCUBE1 plays a role in brain morphogenesis.
SCUBE1 has also been implicated in early craniofacial development in mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항체의 항원 구조 이미지: PA5-70696_SCUBE1_Q6NZL8-1_Rabbit.svg 및 PA5-70696_SCUBE1_Q6NZL8-1_Rabbit_PDP.jpeg)
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