Thermo Fisher Scientific EIF2S1/EIF-2 alpha (EIF2A) Monoclonal Antibody (PCRP-EIF2S1-1C11)
EIF2S1/EIF-2 alpha 단백질을 인식하는 마우스 단클론 항체로, 인간 시료에 반응합니다. Flow Cytometry 및 Peptide Array에 사용 가능하며, 단백질 A/G로 정제된 액상형 제품입니다. 4°C에서 보관하며, 연구용으로만 사용됩니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/10⁶ cells
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-EIF2S1-1C11 |
| Immunogen | Recombinant full-length human EIF2S1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
This antibody is predicted to work in Rat and Zebrafish.
Target Information
EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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