Thermo Fisher Scientific RNF41 Polyclonal Antibody
RNF41 단백질을 인식하는 토끼 폴리클로날 항체로 Western blot 및 IHC(파라핀 절편) 분석에 적합. 인간, 마우스, 랫트 반응성. Protein A로 정제된 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human RNF41 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is composed of a conserved cysteine-rich domain capable of binding two zinc atoms. Proteins containing this conserved domain are generally involved in the ubiquitination pathway of protein degradation.
Nrdp1, also known as RNF41 (RING finger protein 41), SBBI03, or FLRF, is a 317 amino acid protein containing one RING-type zinc finger and one SIAH-type zinc finger. Expressed in testis, ovary, and prostate, Nrdp1 functions as an E3 ubiquitin-protein ligase that transfers ubiquitin from an E2 conjugating enzyme to substrates targeted for degradation. Specifically, Nrdp1 interacts with ErbB-3 and UBPY, targeting them for proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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