Thermo Fisher Scientific NECAB3 Polyclonal Antibody
Human NECAB3 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 신경세포 관련 단백질 연구 및 β-amyloid 생성 조절 연구에 활용 가능.
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NECAB3. Recombinant protein control fragment (Product #RP-108568) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791993 |
Product Specific Information
Immunogen sequence:
SSEAEMQWRL QVNRLQELID QLECKVRAVG PGPHKGGPSW YPPEPGPCWR PGPHSVPSQA PRLEPLREED LAK
Target Information
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L.
This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation.
The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus.
Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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