Thermo Fisher Scientific ULK2 Monoclonal Antibody (1A4)
ULK2 단백질을 인식하는 Mouse monoclonal antibody (Clone 1A4). Western blot 및 ELISA에 적합하며, 인간 시료에 반응. 자가포식 관련 신호전달 연구에 유용. PBS buffer, 무보존제, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A4 |
| Immunogen | ULK2 (AAH34988, 743–843 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
FLRTRTTSVG PSNSGGSLCA MSGRVCVGSP PGPGFGSSPP GAEAAPSLRY VPYGASPPSL EGLITFEAPE LPEETLMERE HTDTLRHLNV MLMFTECVLD L
Target Information
ULK2 (also known as ATG1B) is a serine/threonine protein kinase acting at the upstream step of autophagosome formation. Knockout of ULK2 causes severe defects in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shares high homology with ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200, mediating TOR signaling essential for autophagy. ULK2 is also implicated in early neuronal growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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