Thermo Fisher Scientific SGEF Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2664366

Product Specific Information

Immunogen sequence: ESEVDNDVDSP GSLRRGLRST SYRRAVVSGF DFDSPTSSKK KNRMSQPVLK VVMEDKEKFS SLGRIKKKML KGQGTFDGEE NAVLYQNYKE KALDIDSDEE SEPKEQKSDE KIVIHHKPLR STWSQLSAVK RKGLSQ

Highest antigen sequence identity to the following orthologs - mouse 93%, rat 95%.

Target Information

Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.