Thermo Fisher Scientific HTRA3 Polyclonal Antibody
HTRA3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 적합하며, Human, Mouse, Rat에 반응. 고순도 Affinity Chromatography 정제, -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 334–453 of human HTRA3 (NP_444272.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.06 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855249 |
Product Specific Information
Immunogen sequence:
SDRITRFLTE FQDKQIKDWK KRFIGIRMRT ITPSLVDELK ASNPDFPEVS SGIYVQEVAP NSPSQRGGIQ DGDIIVKVNG RPLVDSSELQ EAVLTESPLL LEVRRGNDDL LFSIAPEVVM
Target Information
HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family and is also known as pregnancy-related serine protease. HtrA3 has two isoforms (long and short) produced by alternative splicing. Similar to HtrA1, HtrA3 binds to various TGF-beta proteins and inhibits the signaling of BMP-4, BMP-2, and TGF-beta 1. It does not inhibit signaling from a constitutively active BMP receptor, indicating inhibition occurs upstream of the cell surface receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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