Thermo Fisher Scientific PACRG Polyclonal Antibody
PACRG 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 단백질에 반응하며, 합성 펩타이드 면역원으로 제작되었습니다. 0.5 mg/mL 농도의 액상 형태이며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human PACRG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606001 |
Product Specific Information
- Peptide sequence: GAIMARCNLD HLGSSDPPTS ASQVAEIIVN SGDGIDYSQQ KRENIGDLIQ
- Sequence homology:
Cow: 100%
Guinea Pig: 93%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 100%
Target Information
PACRG is a protein conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson’s disease. These genes are co-regulated in various tissues and share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson’s disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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