Merck Anti-Protein Disulfide Isomerase (DL-11) antibody produced in rabbit

Anti-Protein Disulfide Isomerase (DL-11) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Anti-Erp58, Anti-PDI, Prolyl 4-hydroxylase subunit β (P4HB)

생물학적 소스

rabbit

Quality Level

200

결합

unconjugated

항체 형태

affinity isolated antibody

antibody product type

primary antibodies

클론

polyclonal

form

buffered aqueous solution

분자량

antigen 57 kDa

species reactivity

mouse, rat, human

포장

antibody small pack of 25 μL

technique(s)

immunoprecipitation (IP): 1-2 μg using RIPA lysate (250-500 μg) of rat NRK cells
indirect immunofluorescence: 2-5 μg/mL using human HeLa cells
western blot (chemiluminescent): 0.1-0.2 μg/mL using whole extract of mouse NIH3T3 cells

UniProt 수납 번호

P07237

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... P4HB(5034)
mouse ... P4hb(18453)
rat ... P4hb(25506)

Protein Disulfide Isomerase is an abundant multifunctional, soluble enzyme (E.C. 5.3.4.1). PDI is expressed in cellular localizations such as the cell surface, cytosol and nucleus. PDI consists of four tandem domains, two of which contain a catalytic site for S-S bond formation. One domain is the main site of noncovalent interaction with other peptides or proteins. PDI has an N-terminal ER signal and C-terminal ER retention KDEL signal sequences.