Merck Monoclonal Anti-Phosphacan antibody produced in mouse
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Monoclonal Anti-Phosphacan antibody produced in mouse
~2 mg/mL, clone 122.2, purified immunoglobulin, buffered aqueous solution
Anti-PTPRB, Anti-Receptor-type Protein-tyrosine phosphatase β
Monoclonal Anti-Phosphacan (mouse IgM isotype) is derived from the hybridoma 122.2 produced by the fusion of mouse myeloma cells (P3X cells) and splenocytes from BALB/c mice immunized with rat brain proteoglycans. Chondroitin sulfate proteoglycans are neural cell adhesion molecules (NCAM) ligands present in the brain extracellular matrix (ECM). Phosphacan protein is expressed mainly in astrocytes and is a ligand for NCAM. Phosphacan is the soluble extracellular domain of the receptor-type transmembrane protein tyrosine phosphatase (RPTPb).
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