Merck Anti-ALS2 (N-terminal region) antibody produced in rabbit

Anti-ALS2 (N-terminal region) antibody produced in rabbit

~1.5 mg/mL, affinity isolated antibody

Anti-ALS2CR6, Anti-ALSJ, Anti-IAHSP, Anti-ALSIN, Anti-PLSJ

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

antibody product type

primary antibodies

클론

polyclonal

form

buffered aqueous solution

분자량

antigen ~185 kDa

포장

antibody small pack of 25 μL

농도

~1.5 mg/mL

technique(s)

indirect immunofluorescence: 2-4 μg/mL using NIH3T3 cells
western blot: 1.5-3.0 μg/mL using HEK-293T cell lysate over expressing human ALS2, and rat cerebellum extract (S1 fraction).

배송 상태

dry ice

저장 온도

−20°C

Gene Information

mouse ... Als2(74018)
rat ... Als2(363235)

Amyotrophic lateral sclerosis (ALS)2 gene codes for 184 kDa alsin protein. Alsin is characterized with the three putative guanine exchange factor (GEF) domains such as, RCC1-like domain (RLD), the Dbl and pleckstrin homology (DH/PH) domain, and a vacuolar protein sorting 9 (VPS9) domain. In addition, ALS2 also contains eight consecutive membrane occupation and recognition nexus (MORN) motifs. ALS2 mRNA is ubiquitously expressed in the CNS and non-neuronal tissues, with the highest expression in the cerebellum and kidney.