Merck Anti-PDGFRα Antibody

Anti-PDGFRα Antibody

Upstate®, from rabbit

생물학적 소스

rabbit

Quality Level

100

항체 형태

affinity purified immunoglobulin

antibody product type

primary antibodies

클론

polyclonal

정제법

affinity chromatography

species reactivity

mouse, human

포장

antibody small pack of 25 μL

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

동형

IgG

NCBI 수납 번호

NM_011058

UniProt 수납 번호

P16234

배송 상태

ambient

Gene Information

human ... PDGFRA(5156)

Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation, and also lead to activation of the Ras, Raf and ERK 1 and 2 pathway.