Merck Anti-Dnmt3b Antibody, clone D3B2-2C1

Anti-Dnmt3b Antibody, clone D3B2-2C1

clone D3B2-2C1, from rat

DNA (cytosine-5)-methyltransferase 3B, Dnmt3b, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB, M.HsaIIIB

Quality Level

100

생물학적 소스

rat

항체 형태

purified immunoglobulin

antibody product type

primary antibodies

클론

D3B2-2C1, monoclonal

species reactivity

human

포장

antibody small pack of 25 μg

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

동형

IgG2bκ

NCBI 수납 번호

NP_001193984

UniProt 수납 번호

Q9UBC3

배송 상태

wet ice

저장 온도

2-8°C

DNA (cytosine-5)-methyltransferase 3B (Dnmt3B) is one of three mammalian enzymes that catalyze the addition of a methyl group to the 5’ carbon of cytosine residues in CpG dinucleotides. The Dnmt3b enzyme is involved in de novo methylation and the establishment of genome-wide DNA methylation patterns during development. DNA methylation has been linked to chromosome stability and gene expression in somatic cells; and to parental imprinting and X-chromosome inactivation in germ cells. Several studies have indicated that DNA methylation patterns are altered in various cancers.