Merck Anti-BRCA1 Antibody, clone BR64

Anti-BRCA1 Antibody, clone BR64

clone BR64, Chemicon®, from mouse

Quality Level

100

생물학적 소스

mouse

항체 형태

purified antibody

antibody product type

primary antibodies

클론

BR64, monoclonal

species reactivity

mouse, human

포장

antibody small pack of 25 μg

manufacturer/tradename

Chemicon®

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

동형

IgG1κ

NCBI 수납 번호

NM_007294.2
NM_007295.2
NM_007296.2
NM_007297.2
NM_007298.2
NM_007299.2
NM_007300.2
NM_007302.2
NM_007303.2
NM_007304.2
NM_007305.2

UniProt 수납 번호

P38398

배송 상태

ambient

저장 온도

2-8°C

Gene Information

human ... BRCA1(672)

The breast cancer susceptibility gene, BRCA1*, is located on chromosome 17 (at q21), and is mutated in the majority of heritable breast cancers. The mutations within the coding region occur throughout the gene with little apparent clustering. The majority of BRCA1 mutations result in shortened BRCA1 gene products, creating a need for an amino-terminal marker. Antibody MAB4132 recognizes both the full-length and mutated (shortened) forms of BRCA1 in breast cancer cell lines. It also recognizes over-expressed protein in transiently transfected Cos cells. A single cross-reacting protein of approximately 27 kDa is also seen upon immunoprecipitation. No other cross-reacting proteins are detected.

BRAC1 is 220kDa.

*BRCA1 is covered under U.S. patents 5,747,282, 5,753,441 and 6,162,897.