Merck Anti-TIN2 antibody, Mouse monoclonal

Anti-TIN2 antibody, Mouse monoclonal

clone TIN30, purified from hybridoma cell culture

Anti-TIN2L, Anti-TERF1 (TRF1)-interacting nuclear factor 2, Anti-TINF2

Quality Level

200

생물학적 소스

mouse

결합

unconjugated

항체 형태

purified from hybridoma cell culture

antibody product type

primary antibodies

클론

TIN30, monoclonal

form

buffered aqueous solution

분자량

antigen ~40 kDa

species reactivity

human

포장

antibody small pack of 25 μL

농도

~1.0 mg/mL

technique(s)

western blot: 0.5-1.0 μg/mL using HeLa cell extract

동형

IgG1

UniProt 수납 번호

Q9BSI4

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... TINF2(26277)

Monoclonal Anti-TIN2 (mouse IgG1 isotype) is derived from the hybridoma TIN-30 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a fragment of human TIN-2, conjugated to keyhole limpet hemocyanin (KLH). The six shelterin subunits are: TRF1, TRF2, and POT1 which directly recognize the TTAGGG repeats, and TIN2, Rap1 and TPP1. TIN2 (TRF-1 interacting nuclear factor 2) is recruited to the telomere through the TRF homology (TRFH) domain of TRF1 and tethers TPP1/POT1 to TRF1 and TRF2.