Merck Anti-DDX6 antibody, Mouse monoclonal

Anti-DDX6 antibody, Mouse monoclonal

Clone

DDX6-34, purified from hybridoma cell culture

Target Information

Probable ATP-dependent RNA helicase DDX6, also known as DEAD box protein 6, HLR2, Oncogene RCK, or ATP-dependent RNA helicase p54.
DDX6 is a conserved member of the DEAD-box RNA helicase family and plays a central role in P-body assembly in mammals. Depletion of DDX6 prevents P-body formation, leading to their disappearance.
It coordinates RNA and ATP helicase binding activities, binds along mRNA, and facilitates recruitment of the decapping complex at the mRNA 5′ end, coupling translational repression and mRNA degradation.

제품 사양

실험 적용(Recommended Applications)

• Immunoblotting (WB): 1–2 μg/mL using human HeLa whole cell extract
• Immunofluorescence (IF): 10–20 μg/mL using human U-2-OS cells

Gene Information

추가 정보

Partial human DDX6 recombinant protein used for antibody generation.