Merck Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&2) antibody, Mouse monoclonal
ERK1/2 활성형 인산화 형태를 인식하는 Mouse monoclonal 항체입니다. MAPK-YT 클론에서 유래하였으며, ERK 활성 루프의 인산화 펩타이드로 면역화된 BALB/c 마우스로부터 생산되었습니다. 세포 신호전달 연구 및 MAPK 활성 검출에 적합합니다.
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Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&2) Antibody, Mouse Monoclonal
Clone MAPK-YT, Purified from Hybridoma Cell Culture
Mitogen-activated protein kinase (MAPK), also known as extracellular signal-regulated kinase (ERK), exists in two isoforms:
- ERK1 (MAPK3) – located on human chromosome 16p11.2
- ERK2 (MAPK1) – located on human chromosome 22q11.2
This Mouse monoclonal antibody (IgG1 isotype) is derived from the MAPK-YT hybridoma, produced by the fusion of mouse myeloma cells (NS1) and splenocytes from BALB/c mice immunized with a synthetic phosphorylated peptide containing amino acids corresponding to the phosphorylated form of the ERK activation loop, conjugated to KLH.
The isotype was determined by a double diffusion immunoassay using Mouse Monoclonal Antibody Isotyping Reagents (Product Number ISO2).
제품 사양
| 항목 | 내용 |
|---|---|
| 제품명 | Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&2) antibody |
| 클론명 | MAPK-YT |
| 항체 유형 | Mouse monoclonal (IgG1) |
| 항원 | Phosphorylated ERK activation loop peptide conjugated to KLH |
| 유래 | BALB/c mouse splenocytes × NS1 myeloma cells |
| 정제 방법 | Purified from hybridoma cell culture |
| 용도 | Detection of activated diphosphorylated ERK1/2 (MAPK) |
| 공급업체 | Merck Sigma |
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