Merck Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&2) antibody, Mouse monoclonal

Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&2) antibody, Mouse monoclonal

clone MAPK-YT, purified from hybridoma cell culture

Monoclonal Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&2)

Mitogen-activated protein kinase (MAPK) are also known as the extracellular signal-regulated kinase (ERKs), they exist in two isoforms namely, ERK1 (MAPK3) and ERK2 (MAPK1). ERK2 is mapped to human chromosome 22q11.2. ERK1 is located on human chromosome 16p11.2.
Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&2) antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the MAPK-YT hybridoma produced by the fusion of mouse myeloma cells (NS1) and splenocytes from BALB/c mice immunized with a synthetic phosphorylated peptide containing amino acids corresponding to the phosphorylated form of ERK-activation loop, conjugated to KLH. The isotype is determined by a double diffusion immunoassay using Mouse Monoclonal Antibody Isotyping Reagents, Product Number ISO2.