Merck Anti-Polyglutamines antibody, Mouse monoclonal

Anti-Polyglutamines antibody, Mouse monoclonal

~2 mg/mL, clone 3B5H10, purified from hybridoma cell culture

Anti-Huntingtin

Quality Level

200

생물학적 소스

mouse

결합

unconjugated

항체 형태

purified from hybridoma cell culture

antibody product type

primary antibodies

클론

3B5H10, monoclonal

form

buffered aqueous solution

species reactivity

human

포장

antibody small pack of 25 μL

농도

~2 mg/mL

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: 1-2 μg/mL using extract of HEK-293T cells transfected with an N-terminal 171 amino acid fragment of human Huntingtin with a 68 glutamine stretch

동형

IgG1

UniProt 수납 번호

P42858

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... HTT(3064)

Abnormal stretch of triplet CAG (or CAA) codon produces a homomeric repeat of glutamine residues beyond the critical threshold and will lead to neurodegenerative disease. Monoclonal mouse anti-polyglutamine antibody can be used to detect poly Q protein expression and in western blot. Monoclonal anti-polyglutamines antibody reacts specifically to homomeric polyglutamines independent of the species.