Merck SILuLite IFNG Interferon Gamma human

SILu™Lite IFNG Interferon Gamma human

recombinant, expressed in HEK 293 cells, MS Protein Standard

Immune interferon, IFN-gamma, IFNγ, Immuneinterferon

Quality Level

200

생물학적 소스

human

재조합

expressed in HEK 293 cells

assay

≥98% (SDS-PAGE)

form

lyophilized powder

효능

≥98% Heavy amino acids incorporation efficiency by MS

분자량

calculated mol wt 17 kDa

technique(s)

mass spectrometry (MS): suitable

적합성

suitable for mass spectrometry (internal calibrator)

UniProt 수납 번호

P01579

저장 온도

−20°C

Gene Information

human ... IFNG(3458)

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. IFNγ is secreted by T helper cells (specifically, Th1 cells), cytotoxic T cells (TC cells) and Natural killer (NK) cells. When combined with other inflammatory cytokines, evaluating the levels of IFNγ can be used as a diagnostic tool in patients with breast cancer or benign prostatic hyperplasia. A recent study evaluated the effect of a cancer vaccine given to patients with colorectal cancer, on the levels of plasma pro-inflammatory cytokines (including IFN-γ). The study concluded that patients achieving stable disease showed increasing levels of plasma inflammatory cytokines.