Merck Mouse IgG1 ELISA Kit

Mouse IgG1 ELISA Kit

species reactivity

mouse

technique(s)

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

배송 상태

wet ice

저장 온도

−20°C

Immunoglobulin G (IgG) is the most prevalent protein found in the human serum. About 10–20% of plasma protein accounts for IgG. IgG1 is the major Ig isotype in murine serum. It resembles human IgG4 functionally. Murine immunoglobulin G1 (IgG1) is capable of blocking the complex formation of IgG2a, IgG2b, and IgG3 with C1q. C1q-mediated complement activation by IgG2a can be blocked by murine IgG1. Because of their likely inhibitory influence on both complement and classical Fcγ receptor (FcγR) activation, murine IgG1 may have the greatest inhibitory capacity toward all other IgG types. The antibody pair provided in this kit recognizes mouse IgG1.