Merck CP-456773 sodium salt

CP-456773 sodium salt

≥98% (HPLC)

CRID3, MCC950, N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide sodium salt, Cytokine release inhibitory drug 3

Quality Level

100

assay

≥98% (HPLC)

form

powder

manufacturer/tradename

Pfizer®

색상

white to beige

solubility

H2O: 20 mg/mL, clear

주관자

Pfizer

저장 온도

room temp

SMILES string

CC(O)(C)C1=COC(S([N-]C(NC2=C(CCC3)C3=CC4=C2CCC4)=O)(=O)=O)=C1.[Na+]

InChI

1S/C20H24N2O5S.Na/c1-20(2,24)14-10-17(27-11-14)28(25,26)22-19(23)21-18-15-7-3-5-12(15)9-13-6-4-8-16(13)18;/h9-11,24H,3-8H2,1-2H3,(H2,21,22,23);/q;+1/p-1

InChI key

LFQQNXFKPNZRFT-UHFFFAOYSA-M

CP-456773 sodium salt has been used :

• In in vivo experiments to study the neuroprotective action of ketogenic diet.
• To study the effect of inhibition of NLRP3 (nod-like receptor protein 3) inflammasome activity on tumor progression in mouse models.
• To study the cholesterol crystal-mediated IL-1b (interleukin-1b) response in placental explants.